Single-molecule spectroscopy exposes hidden states in an enzymatic electron relay

The ability to query enzyme molecules individually is transforming our view of catalytic mechanisms. Quiescin sulfhydryl oxidase (QSOX) is a multidomain catalyst of disulfide-bond formation that relays electrons from substrate cysteines through two redox-active sites to molecular oxygen. The chemica...

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Detalles Bibliográficos
Autores principales: Grossman, Iris, Yuval Aviram, Haim, Armony, Gad, Horovitz, Amnon, Hofmann, Hagen, Haran, Gilad, Fass, Deborah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634331/
https://www.ncbi.nlm.nih.gov/pubmed/26468675
http://dx.doi.org/10.1038/ncomms9624

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634331/
https://www.ncbi.nlm.nih.gov/pubmed/26468675
http://dx.doi.org/10.1038/ncomms9624

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