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Conditional depletion of intellectual disability and Parkinsonism candidate gene ATP6AP2 in fly and mouse induces cognitive impairment and neurodegeneration

ATP6AP2, an essential accessory component of the vacuolar H+ ATPase (V-ATPase), has been associated with intellectual disability (ID) and Parkinsonism. ATP6AP2 has been implicated in several signalling pathways; however, little is known regarding its role in the nervous system. To decipher its funct...

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Detalles Bibliográficos
Autores principales:	Dubos, Aline, Castells-Nobau, Anna, Meziane, Hamid, Oortveld, Merel A.W., Houbaert, Xander, Iacono, Giovanni, Martin, Christelle, Mittelhaeuser, Christophe, Lalanne, Valérie, Kramer, Jamie M., Bhukel, Anuradha, Quentin, Christine, Slabbert, Jan, Verstreken, Patrik, Sigrist, Stefan J., Messaddeq, Nadia, Birling, Marie-Christine, Selloum, Mohammed, Stunnenberg, Henk G., Humeau, Yann, Schenck, Annette, Herault, Yann
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2015
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634377/ https://www.ncbi.nlm.nih.gov/pubmed/26376863 http://dx.doi.org/10.1093/hmg/ddv380

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