Cargando…

Interferon (IFN) and Cellular Immune Response Evoked in RNA-Pattern Sensing During Infection with Hepatitis C Virus (HCV)

Hepatitis C virus (HCV) infects hepatocytes but not dendritic cells (DCs), but DCs effectively mature in response to HCV-infected hepatocytes. Using gene-disrupted mice and hydrodynamic injection strategy, we found the MAVS pathway to be crucial for induction of type III interferons (IFNs) in respon...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nakai, Masato, Oshiumi, Hiroyuki, Funami, Kenji, Okamoto, Masaaki, Matsumoto, Misako, Seya, Tsukasa, Sakamoto, Naoya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634469/ https://www.ncbi.nlm.nih.gov/pubmed/26512676 http://dx.doi.org/10.3390/s151027160

Ejemplares similares

The dataset of proteins specifically interacted with activated TICAM-1
por: Funami, Kenji, et al.
Publicado: (2016)

Double-stranded RNA analog and type I interferon regulate expression of Trem paired receptors in murine myeloid cells
por: Kasamatsu, Jun, et al.
Publicado: (2016)

Zyxin stabilizes RIG-I and MAVS interactions and promotes type I interferon response
por: Kouwaki, Takahisa, et al.
Publicado: (2017)

Interferon-stimulated gene of 20 kDa protein (ISG20) degrades RNA of hepatitis B virus to impede the replication of HBV in vitro and in vivo
por: Leong, Chean Ring, et al.
Publicado: (2016)

Type I Interferon-Independent Dendritic Cell Priming and Antitumor T Cell Activation Induced by a Mycoplasma fermentans Lipopeptide
por: Takeda, Yohei, et al.
Publicado: (2018)

Development of Mouse Hepatocyte Lines Permissive for Hepatitis C Virus (HCV)
por: Aly, Hussein Hassan, et al.
Publicado: (2011)

Pan-Vertebrate Toll-Like Receptors During Evolution
por: Oshiumi, Hiroyuki, et al.
Publicado: (2008)

A Distinct Role of Riplet-Mediated K63-Linked Polyubiquitination of the RIG-I Repressor Domain in Human Antiviral Innate Immune Responses
por: Oshiumi, Hiroyuki, et al.
Publicado: (2013)

Hepatitis C Virus Core Protein Abrogates the DDX3 Function That Enhances IPS-1-Mediated IFN–Beta Induction
por: Oshiumi, Hiroyuki, et al.
Publicado: (2010)

Cross-priming for antitumor CTL induced by soluble Ag + polyI:C depends on the TICAM-1 pathway in mouse CD11c(+)/CD8α(+) dendritic cells
por: Azuma, Masahiro, et al.
Publicado: (2012)

Nucleic Acid Sensors Involved in the Recognition of HBV in the Liver–Specific in vivo Transfection Mouse Models—Pattern Recognition Receptors and Sensors for HBV
por: Leong, Chean Ring, et al.
Publicado: (2015)

UNC93B1 Physically Associates with Human TLR8 and Regulates TLR8-Mediated Signaling
por: Itoh, Hiroki, et al.
Publicado: (2011)

The Anti-Oxidant Ergothioneine Augments the Immunomodulatory Function of TLR Agonists by Direct Action on Macrophages
por: Yoshida, Sumito, et al.
Publicado: (2017)

An embryo-specific expressing TGF-β family protein, growth-differentiation factor 3 (GDF3), augments progression of B16 melanoma
por: Ehira, Nobuyuki, et al.
Publicado: (2010)

TLR3/TICAM-1 signaling in tumor cell RIP3-dependent necroptosis
por: Seya, Tsukasa, et al.
Publicado: (2012)

Correction: an embryo-specific expressing TGF-β family protein, growth-differentiation factor 3 (GDF3), augments progression of B16 melanoma
por: Ehira, Nobuyuki, et al.
Publicado: (2014)

Cell Type-Specific Subcellular Localization of Phospho-TBK1 in Response to Cytoplasmic Viral DNA
por: Suzuki, Takayuki, et al.
Publicado: (2013)

TAMable tumor-associated macrophages in response to innate RNA sensing
por: Seya, Tsukasa, et al.
Publicado: (2012)

Identification of a polyI:C-inducible membrane protein that participates in dendritic cell–mediated natural killer cell activation
por: Ebihara, Takashi, et al.
Publicado: (2010)

Identification of a polyI:C-inducible membrane protein that participates in dendritic cell–mediated natural killer cell activation
por: Ebihara, Takashi, et al.
Publicado: (2015)

cGAMP Promotes Germinal Center Formation and Production of IgA in Nasal-Associated Lymphoid Tissue
por: Takaki, Hiromi, et al.
Publicado: (2017)

RIOK3 keeps MDA5 inactive
por: Takashima, Ken, et al.
Publicado: (2015)

Accessory Factors of Cytoplasmic Viral RNA Sensors Required for Antiviral Innate Immune Response
por: Oshiumi, Hiroyuki, et al.
Publicado: (2016)

The TLR3/TICAM-1 signal constitutively controls spontaneous polyposis through suppression of c-Myc in Apc(Min/+) mice
por: Ono, Junya, et al.
Publicado: (2017)

Toll-like receptor 2 ligand and interferon-γ suppress anti-tumor T cell responses by enhancing the immunosuppressive activity of monocytic myeloid-derived suppressor cells
por: Shime, Hiroaki, et al.
Publicado: (2017)

Toward Establishing an Ideal Adjuvant for Non-Inflammatory Immune Enhancement
por: Seya, Tsukasa, et al.
Publicado: (2022)

Role of Toll-like Receptors in Adjuvant-Augmented Immune Therapies
por: Seya, Tsukasa, et al.
Publicado: (2006)

Tumoricidal efficacy coincides with CD11c up-regulation in antigen-specific CD8(+) T cells during vaccine immunotherapy
por: Takeda, Yohei, et al.
Publicado: (2016)

Toll-Like Receptor 3 Signal in Dendritic Cells Benefits Cancer Immunotherapy
por: Matsumoto, Misako, et al.
Publicado: (2017)

Two Modes of Th1 Polarization Induced by Dendritic-Cell-Priming Adjuvant in Vaccination
por: Seya, Tsukasa, et al.
Publicado: (2023)

Extracellular Vesicles Including Exosomes Regulate Innate Immune Responses to Hepatitis B Virus Infection
por: Kouwaki, Takahisa, et al.
Publicado: (2016)

Anti-oxidative Amino Acid L-ergothioneine Modulates the Tumor Microenvironment to Facilitate Adjuvant Vaccine Immunotherapy
por: Yoshida, Sumito, et al.
Publicado: (2019)

Regulation of interferon signaling and HCV-RNA replication by extracellular matrix
por: Kuwashiro, Takuya, et al.
Publicado: (2018)

TLR2-Dependent Induction of IL-10 and Foxp3(+)CD25(+)CD4(+) Regulatory T Cells Prevents Effective Anti-Tumor Immunity Induced by Pam2 Lipopeptides In Vivo
por: Yamazaki, Sayuri, et al.
Publicado: (2011)

Dendritic Cells from Oral Cavity Induce Foxp3(+) Regulatory T Cells upon Antigen Stimulation
por: Yamazaki, Sayuri, et al.
Publicado: (2012)

Adjuvant for vaccine immunotherapy of cancer – focusing on Toll‐like receptor 2 and 3 agonists for safely enhancing antitumor immunity
por: Seya, Tsukasa, et al.
Publicado: (2015)

Adjuvant immunotherapy for cancer: both dendritic cell-priming and check-point inhibitor blockade are required for immunotherapy
por: SEYA, Tsukasa, et al.
Publicado: (2018)

Regulation of RIG-I Activation by K63-Linked Polyubiquitination
por: Okamoto, Masaaki, et al.
Publicado: (2018)

Effects of Pegylated Interferon Alpha and Ribavirin (pegIFN-α/RBV) Therapeutic Approach on Regulatory T Cells in HCV-Monoinfected and HCV/HIV-Coinfected Patients
por: Grubczak, Kamil, et al.
Publicado: (2021)

Interferon lambda 4 signals via the IFNλ receptor to regulate antiviral activity against HCV and coronaviruses
por: Hamming, Ole J, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_uh3ubj977715nu7cbm5t8b9ato