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HIV-specific CD4-induced Antibodies Mediate Broad and Potent Antibody-dependent Cellular Cytotoxicity Activity and are Commonly Detected in Plasma from HIV-infected Humans

HIV-specific antibodies (Abs) can reduce viral burden by blocking new rounds of infection or by destroying infected cells via activation of effector cells through Fc–FcR interaction. This latter process, referred to as antibody-dependent cellular cytotoxicity (ADCC), has been associated with viral c...

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Detalles Bibliográficos
Autores principales:	Williams, Katherine L., Cortez, Valerie, Dingens, Adam S., Gach, Johannes S., Rainwater, Stephanie, Weis, Julie F., Chen, Xuemin, Spearman, Paul, Forthal, Donald N., Overbaugh, Julie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634620/ https://www.ncbi.nlm.nih.gov/pubmed/26629541 http://dx.doi.org/10.1016/j.ebiom.2015.09.001

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