Addressing health disparities in Hispanic breast cancer: accurate and inexpensive sequencing of BRCA1 and BRCA2

BACKGROUND: Germline mutations in the BRCA1 and BRCA2 genes account for 20–25 % of inherited breast cancers and about 10 % of all breast cancer cases. Detection of BRCA mutation carriers can lead to therapeutic interventions such as mastectomy, oophorectomy, hormonal prevention therapy, improved scr...

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Detalles Bibliográficos
Autores principales: Dean, Michael, Boland, Joseph, Yeager, Meredith, Im, Kate M., Garland, Lisa, Rodriguez-Herrera, Maria, Perez, Mylen, Mitchell, Jason, Roberson, David, Jones, Kristine, Lee, Hyo Jung, Eggebeen, Rebecca, Sawitzke, Julie, Bass, Sara, Zhang, Xijun, Robles, Vivian, Hollis, Celia, Barajas, Claudia, Rath, Edna, Arentz, Candy, Figueroa, Jose A., Nguyen, Diane D., Nahleh, Zeina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634732/
https://www.ncbi.nlm.nih.gov/pubmed/26543556
http://dx.doi.org/10.1186/s13742-015-0088-z

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