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Application of Nanotrap technology for high sensitivity measurement of urinary outer surface protein A carboxyl-terminus domain in early stage Lyme borreliosis

OBJECTIVES: Prompt antibiotic treatment of early stage Lyme borreliosis (LB) prevents progression to severe multisystem disease. There is a clinical need to improve the diagnostic specificity of early stage Lyme assays in the period prior to the mounting of a robust serology response. Using a novel...

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Detalles Bibliográficos
Autores principales: Magni, Ruben, Espina, Benjamin H., Shah, Ketul, Lepene, Benjamin, Mayuga, Christine, Douglas, Temple A., Espina, Virginia, Rucker, Sally, Dunlap, Ross, Petricoin, Emanuel F. III, Kilavos, Mary Frekko, Poretz, Donald M., Irwin, Gilbert R., Shor, Samuel M., Liotta, Lance A., Luchini, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634744/
https://www.ncbi.nlm.nih.gov/pubmed/26537892
http://dx.doi.org/10.1186/s12967-015-0701-z