Periostin is critical for improving the therapeutic properties of adipocyte-derived stem cells

Periostin is a matricellular protein that is reactivated during tissue damage and repair and has been shown to be a critical regulator of multiple biological pathways involved in the repair of tissue after myocardial infarction, peripheral vascular disease, and skin wounds. The tissue repair propert...

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Detalles Bibliográficos
Autores principales: Chow, Theresa, Rogers, Ian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634790/
https://www.ncbi.nlm.nih.gov/pubmed/26537950
http://dx.doi.org/10.1186/s13287-015-0215-x
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author Chow, Theresa
Rogers, Ian M.
author_facet Chow, Theresa
Rogers, Ian M.
author_sort Chow, Theresa
collection PubMed
description Periostin is a matricellular protein that is reactivated during tissue damage and repair and has been shown to be a critical regulator of multiple biological pathways involved in the repair of tissue after myocardial infarction, peripheral vascular disease, and skin wounds. The tissue repair properties attributed to periostin make it an ideal candidate to enhance the therapeutic properties of donor cells such as mesenchymal stem cells from adipocyte tissue. In a recent article in Stem Cell Research & Therapy, Qin et al. demonstrated enhanced therapeutic properties of adipocyte-derived stem cells by genetically engineering them to express periostin.
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spelling pubmed-46347902015-11-06 Periostin is critical for improving the therapeutic properties of adipocyte-derived stem cells Chow, Theresa Rogers, Ian M. Stem Cell Res Ther Commentary Periostin is a matricellular protein that is reactivated during tissue damage and repair and has been shown to be a critical regulator of multiple biological pathways involved in the repair of tissue after myocardial infarction, peripheral vascular disease, and skin wounds. The tissue repair properties attributed to periostin make it an ideal candidate to enhance the therapeutic properties of donor cells such as mesenchymal stem cells from adipocyte tissue. In a recent article in Stem Cell Research & Therapy, Qin et al. demonstrated enhanced therapeutic properties of adipocyte-derived stem cells by genetically engineering them to express periostin. BioMed Central 2015-11-04 /pmc/articles/PMC4634790/ /pubmed/26537950 http://dx.doi.org/10.1186/s13287-015-0215-x Text en © Chow and Rogers. 2015 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Commentary
Chow, Theresa
Rogers, Ian M.
Periostin is critical for improving the therapeutic properties of adipocyte-derived stem cells
title Periostin is critical for improving the therapeutic properties of adipocyte-derived stem cells
title_full Periostin is critical for improving the therapeutic properties of adipocyte-derived stem cells
title_fullStr Periostin is critical for improving the therapeutic properties of adipocyte-derived stem cells
title_full_unstemmed Periostin is critical for improving the therapeutic properties of adipocyte-derived stem cells
title_short Periostin is critical for improving the therapeutic properties of adipocyte-derived stem cells
title_sort periostin is critical for improving the therapeutic properties of adipocyte-derived stem cells
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634790/
https://www.ncbi.nlm.nih.gov/pubmed/26537950
http://dx.doi.org/10.1186/s13287-015-0215-x
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