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TLE6 mutation causes the earliest known human embryonic lethality

BACKGROUND: Embryonic lethality is a recognized phenotypic expression of individual gene mutations in model organisms. However, identifying embryonic lethal genes in humans is challenging, especially when the phenotype is manifested at the preimplantation stage. RESULTS: In an ongoing effort to expl...

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Detalles Bibliográficos
Autores principales:	Alazami, Anas M., Awad, Salma M., Coskun, Serdar, Al-Hassan, Saad, Hijazi, Hadia, Abdulwahab, Firdous M., Poizat, Coralie, Alkuraya, Fowzan S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634911/ https://www.ncbi.nlm.nih.gov/pubmed/26537248 http://dx.doi.org/10.1186/s13059-015-0792-0

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