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A re-randomisation design for clinical trials

BACKGROUND: Recruitment to clinical trials is often problematic, with many trials failing to recruit to their target sample size. As a result, patient care may be based on suboptimal evidence from underpowered trials or non-randomised studies. METHODS: For many conditions patients will require treat...

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Detalles Bibliográficos
Autores principales: Kahan, Brennan C, Forbes, Andrew B, Doré, Caroline J, Morris, Tim P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634916/
https://www.ncbi.nlm.nih.gov/pubmed/26541982
http://dx.doi.org/10.1186/s12874-015-0082-2