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A re-randomisation design for clinical trials
BACKGROUND: Recruitment to clinical trials is often problematic, with many trials failing to recruit to their target sample size. As a result, patient care may be based on suboptimal evidence from underpowered trials or non-randomised studies. METHODS: For many conditions patients will require treat...
Autores principales: | Kahan, Brennan C, Forbes, Andrew B, Doré, Caroline J, Morris, Tim P |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634916/ https://www.ncbi.nlm.nih.gov/pubmed/26541982 http://dx.doi.org/10.1186/s12874-015-0082-2 |
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