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Pleiotropic Effects of Immune Responses Explain Variation in the Prevalence of Fibroproliferative Diseases

Many diseases are differentially distributed among human populations. Differential selection on genetic variants in ancestral environments that coincidentally predispose to disease can be an underlying cause of these unequal prevalence patterns. Selected genes may be pleiotropic, affecting multiple...

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Detalles Bibliográficos
Autores principales:	Russell, Shirley B., Smith, Joan C., Huang, Minjun, Trupin, Joel S., Williams, Scott M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634921/ https://www.ncbi.nlm.nih.gov/pubmed/26540410 http://dx.doi.org/10.1371/journal.pgen.1005568

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