Dissecting Long-Term Glucose Metabolism Identifies New Susceptibility Period for Metabolic Dysfunction in Aged Mice

Metabolic disorders, like diabetes and obesity, are pathogenic outcomes of imbalance in glucose metabolism. Nutrient excess and mitochondrial imbalance are implicated in dysfunctional glucose metabolism with age. We used conplastic mouse strains with defined mitochondrial DNA (mtDNA) mutations on a...

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Detalles Bibliográficos
Autores principales: Chauhan, Anuradha, Weiss, Heike, Koch, Franziska, Ibrahim, Saleh M., Vera, Julio, Wolkenhauer, Olaf, Tiedge, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634931/
https://www.ncbi.nlm.nih.gov/pubmed/26540285
http://dx.doi.org/10.1371/journal.pone.0140858

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