Development of a Novel PET Tracer [(18)F]AlF-NOTA-C6 Targeting MMP2 for Tumor Imaging

BACKGROUND AND OBJECTIVE: The overexpression of gelatinases, that is, matrix metalloproteinase MMP2 and MMP9, has been associated with tumor progression, invasion, and metastasis. To image MMP2 in tumors, we developed a novel ligand termed [(18)F]AlF-NOTA-C6, with consideration that: c(KAHWGFTLD)NH(...

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Detalles Bibliográficos
Autores principales: Liu, Qinghua, Pan, Donghui, Cheng, Chao, Zhang, Dazhi, Zhang, Anyu, Wang, Lizhen, Jiang, Hongdie, Wang, Tao, Liu, Hongrui, Xu, Yuping, Yang, Runlin, Chen, Fei, Yang, Min, Zuo, Changjing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634933/
https://www.ncbi.nlm.nih.gov/pubmed/26540114
http://dx.doi.org/10.1371/journal.pone.0141668

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634933/
https://www.ncbi.nlm.nih.gov/pubmed/26540114
http://dx.doi.org/10.1371/journal.pone.0141668

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