Targeting HIV Reservoir in Infected CD4 T Cells by Dual-Affinity Re-targeting Molecules (DARTs) that Bind HIV Envelope and Recruit Cytotoxic T Cells

HIV reservoirs and production of viral antigens are not eliminated in chronically infected participants treated with combination antiretroviral therapy (cART). Novel therapeutic strategies aiming at viral reservoir elimination are needed to address chronic immune dysfunction and non-AIDS morbidities...

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Detalles Bibliográficos
Autores principales: Sloan, Derek D., Lam, Chia-Ying Kao, Irrinki, Alivelu, Liu, Liqin, Tsai, Angela, Pace, Craig S., Kaur, Jasmine, Murry, Jeffrey P., Balakrishnan, Mini, Moore, Paul A., Johnson, Syd, Nordstrom, Jeffrey L., Cihlar, Tomas, Koenig, Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634948/
https://www.ncbi.nlm.nih.gov/pubmed/26539983
http://dx.doi.org/10.1371/journal.ppat.1005233

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