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The Prevalence of Mild Cognitive Impairment in Diverse Geographical and Ethnocultural Regions: The COSMIC Collaboration
BACKGROUND: Changes in criteria and differences in populations studied and methodology have produced a wide range of prevalence estimates for mild cognitive impairment (MCI). METHODS: Uniform criteria were applied to harmonized data from 11 studies from USA, Europe, Asia and Australia, and MCI preva...
| Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634954/ https://www.ncbi.nlm.nih.gov/pubmed/26539987 http://dx.doi.org/10.1371/journal.pone.0142388 |
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| author | Sachdev, Perminder S. Lipnicki, Darren M. Kochan, Nicole A. Crawford, John D. Thalamuthu, Anbupalam Andrews, Gavin Brayne, Carol Matthews, Fiona E. Stephan, Blossom C. M. Lipton, Richard B. Katz, Mindy J. Ritchie, Karen Carrière, Isabelle Ancelin, Marie-Laure Lam, Linda C. W. Wong, Candy H. Y. Fung, Ada W. T. Guaita, Antonio Vaccaro, Roberta Davin, Annalisa Ganguli, Mary Dodge, Hiroko Hughes, Tiffany Anstey, Kaarin J. Cherbuin, Nicolas Butterworth, Peter Ng, Tze Pin Gao, Qi Reppermund, Simone Brodaty, Henry Schupf, Nicole Manly, Jennifer Stern, Yaakov Lobo, Antonio Lopez-Anton, Raúl Santabárbara, Javier |
| author_facet | Sachdev, Perminder S. Lipnicki, Darren M. Kochan, Nicole A. Crawford, John D. Thalamuthu, Anbupalam Andrews, Gavin Brayne, Carol Matthews, Fiona E. Stephan, Blossom C. M. Lipton, Richard B. Katz, Mindy J. Ritchie, Karen Carrière, Isabelle Ancelin, Marie-Laure Lam, Linda C. W. Wong, Candy H. Y. Fung, Ada W. T. Guaita, Antonio Vaccaro, Roberta Davin, Annalisa Ganguli, Mary Dodge, Hiroko Hughes, Tiffany Anstey, Kaarin J. Cherbuin, Nicolas Butterworth, Peter Ng, Tze Pin Gao, Qi Reppermund, Simone Brodaty, Henry Schupf, Nicole Manly, Jennifer Stern, Yaakov Lobo, Antonio Lopez-Anton, Raúl Santabárbara, Javier |
| author_sort | Sachdev, Perminder S. |
| collection | PubMed |
| description | BACKGROUND: Changes in criteria and differences in populations studied and methodology have produced a wide range of prevalence estimates for mild cognitive impairment (MCI). METHODS: Uniform criteria were applied to harmonized data from 11 studies from USA, Europe, Asia and Australia, and MCI prevalence estimates determined using three separate definitions of cognitive impairment. RESULTS: The published range of MCI prevalence estimates was 5.0%–36.7%. This was reduced with all cognitive impairment definitions: performance in the bottom 6.681% (3.2%–10.8%); Clinical Dementia Rating of 0.5 (1.8%–14.9%); Mini-Mental State Examination score of 24–27 (2.1%–20.7%). Prevalences using the first definition were 5.9% overall, and increased with age (P < .001) but were unaffected by sex or the main races/ethnicities investigated (Whites and Chinese). Not completing high school increased the likelihood of MCI (P ≤ .01). CONCLUSION: Applying uniform criteria to harmonized data greatly reduced the variation in MCI prevalence internationally. |
| format | Online Article Text |
| id | pubmed-4634954 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2015 |
| publisher | Public Library of Science |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-46349542015-11-13 The Prevalence of Mild Cognitive Impairment in Diverse Geographical and Ethnocultural Regions: The COSMIC Collaboration Sachdev, Perminder S. Lipnicki, Darren M. Kochan, Nicole A. Crawford, John D. Thalamuthu, Anbupalam Andrews, Gavin Brayne, Carol Matthews, Fiona E. Stephan, Blossom C. M. Lipton, Richard B. Katz, Mindy J. Ritchie, Karen Carrière, Isabelle Ancelin, Marie-Laure Lam, Linda C. W. Wong, Candy H. Y. Fung, Ada W. T. Guaita, Antonio Vaccaro, Roberta Davin, Annalisa Ganguli, Mary Dodge, Hiroko Hughes, Tiffany Anstey, Kaarin J. Cherbuin, Nicolas Butterworth, Peter Ng, Tze Pin Gao, Qi Reppermund, Simone Brodaty, Henry Schupf, Nicole Manly, Jennifer Stern, Yaakov Lobo, Antonio Lopez-Anton, Raúl Santabárbara, Javier PLoS One Research Article BACKGROUND: Changes in criteria and differences in populations studied and methodology have produced a wide range of prevalence estimates for mild cognitive impairment (MCI). METHODS: Uniform criteria were applied to harmonized data from 11 studies from USA, Europe, Asia and Australia, and MCI prevalence estimates determined using three separate definitions of cognitive impairment. RESULTS: The published range of MCI prevalence estimates was 5.0%–36.7%. This was reduced with all cognitive impairment definitions: performance in the bottom 6.681% (3.2%–10.8%); Clinical Dementia Rating of 0.5 (1.8%–14.9%); Mini-Mental State Examination score of 24–27 (2.1%–20.7%). Prevalences using the first definition were 5.9% overall, and increased with age (P < .001) but were unaffected by sex or the main races/ethnicities investigated (Whites and Chinese). Not completing high school increased the likelihood of MCI (P ≤ .01). CONCLUSION: Applying uniform criteria to harmonized data greatly reduced the variation in MCI prevalence internationally. Public Library of Science 2015-11-05 /pmc/articles/PMC4634954/ /pubmed/26539987 http://dx.doi.org/10.1371/journal.pone.0142388 Text en © 2015 Sachdev et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited. |
| spellingShingle | Research Article Sachdev, Perminder S. Lipnicki, Darren M. Kochan, Nicole A. Crawford, John D. Thalamuthu, Anbupalam Andrews, Gavin Brayne, Carol Matthews, Fiona E. Stephan, Blossom C. M. Lipton, Richard B. Katz, Mindy J. Ritchie, Karen Carrière, Isabelle Ancelin, Marie-Laure Lam, Linda C. W. Wong, Candy H. Y. Fung, Ada W. T. Guaita, Antonio Vaccaro, Roberta Davin, Annalisa Ganguli, Mary Dodge, Hiroko Hughes, Tiffany Anstey, Kaarin J. Cherbuin, Nicolas Butterworth, Peter Ng, Tze Pin Gao, Qi Reppermund, Simone Brodaty, Henry Schupf, Nicole Manly, Jennifer Stern, Yaakov Lobo, Antonio Lopez-Anton, Raúl Santabárbara, Javier The Prevalence of Mild Cognitive Impairment in Diverse Geographical and Ethnocultural Regions: The COSMIC Collaboration |
| title | The Prevalence of Mild Cognitive Impairment in Diverse Geographical and Ethnocultural Regions: The COSMIC Collaboration |
| title_full | The Prevalence of Mild Cognitive Impairment in Diverse Geographical and Ethnocultural Regions: The COSMIC Collaboration |
| title_fullStr | The Prevalence of Mild Cognitive Impairment in Diverse Geographical and Ethnocultural Regions: The COSMIC Collaboration |
| title_full_unstemmed | The Prevalence of Mild Cognitive Impairment in Diverse Geographical and Ethnocultural Regions: The COSMIC Collaboration |
| title_short | The Prevalence of Mild Cognitive Impairment in Diverse Geographical and Ethnocultural Regions: The COSMIC Collaboration |
| title_sort | prevalence of mild cognitive impairment in diverse geographical and ethnocultural regions: the cosmic collaboration |
| topic | Research Article |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634954/ https://www.ncbi.nlm.nih.gov/pubmed/26539987 http://dx.doi.org/10.1371/journal.pone.0142388 |
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