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Targeting the notch pathway: A potential therapeutic approach for desmoid tumors
BACKGROUND: Desmoid tumors (DTs) are rare mesenchymal lesions that can recur repeatedly. When it is feasible, DTs are surgically resected; however, this often results in high recurrence rates. Recently, treatment with PF‐03084014, a potent γ‐secretase inhibitor, has been shown to have antitumor acti...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635059/ https://www.ncbi.nlm.nih.gov/pubmed/26349011 http://dx.doi.org/10.1002/cncr.29564 |