IL-37b gene transfer enhances the therapeutic efficacy of mesenchumal stromal cells in DSS-induced colitis mice

AIM: To investigate whether the transfer of the IL-37b gene, a newly identified inhibitor of both innate and adaptive immunity, could improve the therapeutic efficacy of mesenchumal stromal cells (MSCs) in inflammatory bowel disease (IBD). METHODS: The expression of IL-37 in biopsied specimens of th...

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Detalles Bibliográficos
Autores principales: Wang, Wei-qiang, Dong, Kui, Zhou, Lu, Jiao, Guo-hui, Zhu, Cong-zhong, Li, Wen-wen, Yu, Gang, Wu, Wan-tong, Chen, Song, Sun, Zhi-na, Wang, Yu-ming, Liu, Wen-tian, Zhang, Jie, Wang, Bang-mao, Feng, Xiao-ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635324/
https://www.ncbi.nlm.nih.gov/pubmed/26190499
http://dx.doi.org/10.1038/aps.2015.51

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