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Gelsemine alleviates both neuropathic pain and sleep disturbance in partial sciatic nerve ligation mice
AIM: Gelsemine, an alkaloid from the Chinese herb Gelsemium elegans (Gardn & Champ) Benth., is effective in mitigating chronic pain in rats. In the present study we investigated whether the alkaloid improved sleep disturbance, the most common comorbid symptoms of chronic pain, in a mouse model o...
Autores principales: | Wu, Yu-er, Li, Ya-dong, Luo, Yan-jia, Wang, Tian-xiao, Wang, Hui-jing, Chen, Shuo-nan, Qu, Wei-min, Huang, Zhi-li |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635333/ https://www.ncbi.nlm.nih.gov/pubmed/26388157 http://dx.doi.org/10.1038/aps.2015.86 |
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