Targeting extra-oral bitter taste receptors modulates gastrointestinal motility with effects on satiation

Bitter taste receptors (TAS2Rs) are present in extra-oral tissues, including gut endocrine cells. This study explored the presence and mechanism of action of TAS2R agonists on gut smooth muscle in vitro and investigated functional effects of intra-gastric administration of TAS2R agonists on gastric...

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Detalles Bibliográficos
Autores principales: Avau, Bert, Rotondo, Alessandra, Thijs, Theo, Andrews, Christopher N., Janssen, Pieter, Tack, Jan, Depoortere, Inge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635351/
https://www.ncbi.nlm.nih.gov/pubmed/26541810
http://dx.doi.org/10.1038/srep15985

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