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Preventive effect of oral goshajinkigan on chronic oxaliplatin-induced hypoesthesia in rats

Oxaliplatin, a widely used chemotherapeutic agent, induces peripheral neuropathy that manifests itself as two distinct phases: acute cold hyperesthesia and chronic peripheral hypoesthesia/dysesthesia. The latter is a serious dose-limiting side effect that can often lead to withdrawal of treatment. W...

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Detalles Bibliográficos
Autores principales:	Kono, Toru, Suzuki, Yasuyuki, Mizuno, Keita, Miyagi, Chika, Omiya, Yuji, Sekine, Hitomi, Mizuhara, Yasuharu, Miyano, Kanako, Kase, Yoshio, Uezono, Yasuhito
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635352/ https://www.ncbi.nlm.nih.gov/pubmed/26542342 http://dx.doi.org/10.1038/srep16078

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