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How individual participant data meta-analyses have influenced trial design, conduct, and analysis

OBJECTIVES: To demonstrate how individual participant data (IPD) meta-analyses have impacted directly on the design and conduct of trials and highlight other advantages IPD might offer. STUDY DESIGN AND SETTING: Potential examples of the impact of IPD meta-analyses on trials were identified at an in...

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Detalles Bibliográficos
Autores principales: Tierney, Jayne F., Pignon, Jean-Pierre, Gueffyier, Francois, Clarke, Mike, Askie, Lisa, Vale, Claire L., Burdett, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635379/
https://www.ncbi.nlm.nih.gov/pubmed/26186982
http://dx.doi.org/10.1016/j.jclinepi.2015.05.024