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Synthetic Tet-inducible artificial microRNAs targeting β-catenin or HIF-1α inhibit malignant phenotypes of bladder cancer cells T24 and 5637

Ribonucleic acid interference (RNAi) based on microRNA (miRNA) may provide efficient and safe therapeutic opportunities. However, natural microRNAs can not easily be regulated and usually cause few phenotypic changes. Using the engineering principles of synthetic biology, we provided a novel and sta...

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Detalles Bibliográficos
Autores principales:	Zhan, Yonghao, Liu, Yuchen, Lin, Junhao, Fu, Xing, Zhuang, Chengle, Liu, Li, Xu, Wen, Li, Jianfa, Chen, Mingwei, Zhao, Guoping, Huang, Weiren, Cai, Zhiming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635424/ https://www.ncbi.nlm.nih.gov/pubmed/26541358 http://dx.doi.org/10.1038/srep16177

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