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Albumin administration prevents neurological damage and death in a mouse model of severe neonatal hyperbilirubinemia
Therapies to prevent severe neonatal unconjugated hyperbilirubinemia and kernicterus are phototherapy and, in unresponsive cases, exchange transfusion, which has significant morbidity and mortality risks. Neurotoxicity is caused by the fraction of unconjugated bilirubin not bound to albumin (free bi...
Autores principales: | Vodret, Simone, Bortolussi, Giulia, Schreuder, Andrea B., Jašprová, Jana, Vitek, Libor, Verkade, Henkjan J., Muro, Andrés F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635426/ https://www.ncbi.nlm.nih.gov/pubmed/26541892 http://dx.doi.org/10.1038/srep16203 |
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