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Permissivity of primary hepatocytes and hepatoma cell lines to support hepatitis C virus infection

The major cell type supporting hepatitis C virus (HCV) infection is the hepatocyte; however, most reports studying viral entry and replication utilize transformed hepatoma cell lines. We demonstrate that HCV pseudoparticles (HCVpp) infect primary hepatocytes with comparable rates to hepatoma cells,...

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Detalles Bibliográficos
Autores principales:	Wilson, Garrick K., Farquhar, Michelle J., Meredith, Luke, Dhawan, Anil, Mitry, Ragai, Balfe, Peter, McKeating, Jane A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Society for General Microbiology 2015
Materias:	Animal
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635487/ https://www.ncbi.nlm.nih.gov/pubmed/25667327 http://dx.doi.org/10.1099/vir.0.000085

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