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Permissivity of primary hepatocytes and hepatoma cell lines to support hepatitis C virus infection
The major cell type supporting hepatitis C virus (HCV) infection is the hepatocyte; however, most reports studying viral entry and replication utilize transformed hepatoma cell lines. We demonstrate that HCV pseudoparticles (HCVpp) infect primary hepatocytes with comparable rates to hepatoma cells,...
Autores principales: | Wilson, Garrick K., Farquhar, Michelle J., Meredith, Luke, Dhawan, Anil, Mitry, Ragai, Balfe, Peter, McKeating, Jane A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for General Microbiology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635487/ https://www.ncbi.nlm.nih.gov/pubmed/25667327 http://dx.doi.org/10.1099/vir.0.000085 |
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