Recombinase-based conditional and reversible gene regulation via XTR alleles

Synthetic biological tools that enable precise regulation of gene function within in vivo systems have enormous potential to discern gene function in diverse physiological settings. Here we report the development and characterization of a synthetic gene switch that, when targeted in the mouse germli...

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Detalles Bibliográficos
Autores principales: Robles-Oteiza, Camila, Taylor, Sarah, Yates, Travis, Cicchini, Michelle, Lauderback, Brian, Cashman, Christopher R., Burds, Aurora A., Winslow, Monte M., Jacks, Tyler, Feldser, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635517/
https://www.ncbi.nlm.nih.gov/pubmed/26537451
http://dx.doi.org/10.1038/ncomms9783

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635517/
https://www.ncbi.nlm.nih.gov/pubmed/26537451
http://dx.doi.org/10.1038/ncomms9783

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