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Recombinase-based conditional and reversible gene regulation via XTR alleles
Synthetic biological tools that enable precise regulation of gene function within in vivo systems have enormous potential to discern gene function in diverse physiological settings. Here we report the development and characterization of a synthetic gene switch that, when targeted in the mouse germli...
Autores principales: | Robles-Oteiza, Camila, Taylor, Sarah, Yates, Travis, Cicchini, Michelle, Lauderback, Brian, Cashman, Christopher R., Burds, Aurora A., Winslow, Monte M., Jacks, Tyler, Feldser, David M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635517/ https://www.ncbi.nlm.nih.gov/pubmed/26537451 http://dx.doi.org/10.1038/ncomms9783 |
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