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Autoregulatory CD8 T cells depend on cognate antigen recognition and CD4/CD8 myelin determinants

OBJECTIVE: To determine the antigenic determinants and specific molecular requirements for the generation of autoregulatory neuroantigen-specific CD8(+) T cells in models of multiple sclerosis (MS). METHODS: We have previously shown that MOG35-55-specific CD8(+) T cells suppress experimental autoimm...

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Detalles Bibliográficos
Autores principales:	Ortega, Sterling B., Kashi, Venkatesh P., Cunnusamy, Khrishen, Franco, Jorge, Karandikar, Nitin J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635551/ https://www.ncbi.nlm.nih.gov/pubmed/26587555 http://dx.doi.org/10.1212/NXI.0000000000000170

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