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Complement Evasion Mediated by Enhancement of Captured Factor H: Implications for Protection of Self-Surfaces from Complement

In an attempt to evade annihilation by the vertebrate complement system, many microbes capture factor H (FH), the key soluble complement-regulating protein in human plasma. However, FH is normally an active complement suppressor exclusively on self-surfaces and this selective action of FH is pivotal...

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Detalles Bibliográficos
Autores principales:	Herbert, Andrew P., Makou, Elisavet, Chen, Zhuo A., Kerr, Heather, Richards, Anna, Rappsilber, Juri, Barlow, Paul N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AAI 2015
Materias:	Molecular and Structural Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635569/ https://www.ncbi.nlm.nih.gov/pubmed/26459349 http://dx.doi.org/10.4049/jimmunol.1501388

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