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Mechanistic Target of Rapamycin Complex 1/S6 Kinase 1 Signals Influence T Cell Activation Independently of Ribosomal Protein S6 Phosphorylation

Ag-dependent activation of naive T cells induces dramatic changes in cellular metabolism that are essential for cell growth, division, and differentiation. In recent years, the serine/threonine kinase mechanistic target of rapamycin (mTOR) has emerged as a key integrator of signaling pathways that r...

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Detalles Bibliográficos
Autores principales:	Salmond, Robert J., Brownlie, Rebecca J., Meyuhas, Oded, Zamoyska, Rose
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AAI 2015
Materias:	Antigen Recognition and Responses
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635570/ https://www.ncbi.nlm.nih.gov/pubmed/26453749 http://dx.doi.org/10.4049/jimmunol.1501473

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