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Targeting protein arginine methyltransferase 5 inhibits human hepatocellular carcinoma growth via the downregulation of beta-catenin

BACKGROUND: Protein arginine methyltransferase 5 (PRMT5), a type II PRMT, is highly expressed in some tumors, but its role in hepatocellular carcinoma (HCC) is still unknown. METHODS: PRMT5 level in HCC specimens was determined by immunohistochemical staining and the association with clinicopatholog...

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Detalles Bibliográficos
Autores principales:	Zhang, Baolai, Dong, Shuhong, Li, Zhongxin, Lu, Li, Zhang, Su, Chen, Xue, Cen, Xiaobo, Wu, Yongjie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635578/ https://www.ncbi.nlm.nih.gov/pubmed/26541651 http://dx.doi.org/10.1186/s12967-015-0721-8

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