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Aluminum Phosphide Poisoning-Related Deaths in Tehran, Iran, 2006 to 2013

Metal phosphides such as aluminum phosphide are potent insecticides. This highly toxic substance is used for rice and other grains protection in Iran. Due to its high toxicity potential and easy availability, it is widely used as a suicide poison. This substance has no effective antidote and the inc...

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Autores principales: Etemadi-Aleagha, Afshar, Akhgari, Maryam, Iravani, Fariba Sardari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635777/
https://www.ncbi.nlm.nih.gov/pubmed/26402837
http://dx.doi.org/10.1097/MD.0000000000001637
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author Etemadi-Aleagha, Afshar
Akhgari, Maryam
Iravani, Fariba Sardari
author_facet Etemadi-Aleagha, Afshar
Akhgari, Maryam
Iravani, Fariba Sardari
author_sort Etemadi-Aleagha, Afshar
collection PubMed
description Metal phosphides such as aluminum phosphide are potent insecticides. This highly toxic substance is used for rice and other grains protection in Iran. Due to its high toxicity potential and easy availability, it is widely used as a suicide poison. This substance has no effective antidote and the incidence of deaths due to its poisoning is increasing day by day in Iran. The present study was conducted to show the increasing incidence of fatal aluminum phosphide poisoning and its toxicological and forensic aspects in an 8-year study, 2006 to 2013. Autopsy sheets were reviewed and cases with the history of aluminum phosphide poisoning were selected. Toxicological analysis results, demographic and necroscopic examination findings were studied. A total of 51.8% of studied cases were female. Most of the cases were between 10 and 40 years old. The manner of death was self-poisoning in 85% of cases. Morphine, ethanol, and amitriptyline were the most common additional drugs detected in toxicological analysis. The incidence of fatal aluminum phosphide poisoning cases referred for phosphine analysis was 5.22 and 37.02 per million of population of Tehran in 2006 and 2013, respectively. The results of this study showed that in spite of ban and restrictions, there was a dramatic increase in the incidence of fatal aluminum phosphide poisoning in Tehran from 2006 to 2013. Safety alert should be highlighted in training program for all population groups about the toxic effects of aluminum phosphide tablets.
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spelling pubmed-46357772015-11-30 Aluminum Phosphide Poisoning-Related Deaths in Tehran, Iran, 2006 to 2013 Etemadi-Aleagha, Afshar Akhgari, Maryam Iravani, Fariba Sardari Medicine (Baltimore) 7200 Metal phosphides such as aluminum phosphide are potent insecticides. This highly toxic substance is used for rice and other grains protection in Iran. Due to its high toxicity potential and easy availability, it is widely used as a suicide poison. This substance has no effective antidote and the incidence of deaths due to its poisoning is increasing day by day in Iran. The present study was conducted to show the increasing incidence of fatal aluminum phosphide poisoning and its toxicological and forensic aspects in an 8-year study, 2006 to 2013. Autopsy sheets were reviewed and cases with the history of aluminum phosphide poisoning were selected. Toxicological analysis results, demographic and necroscopic examination findings were studied. A total of 51.8% of studied cases were female. Most of the cases were between 10 and 40 years old. The manner of death was self-poisoning in 85% of cases. Morphine, ethanol, and amitriptyline were the most common additional drugs detected in toxicological analysis. The incidence of fatal aluminum phosphide poisoning cases referred for phosphine analysis was 5.22 and 37.02 per million of population of Tehran in 2006 and 2013, respectively. The results of this study showed that in spite of ban and restrictions, there was a dramatic increase in the incidence of fatal aluminum phosphide poisoning in Tehran from 2006 to 2013. Safety alert should be highlighted in training program for all population groups about the toxic effects of aluminum phosphide tablets. Wolters Kluwer Health 2015-09-25 /pmc/articles/PMC4635777/ /pubmed/26402837 http://dx.doi.org/10.1097/MD.0000000000001637 Text en Copyright © 2015 Wolters Kluwer Health, Inc. All rights reserved. http://creativecommons.org/licenses/by-nc-nd/4.0 This is an open access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives License 4.0, where it is permissible to download, share and reproduce the work in any medium, provided it is properly cited. The work cannot be changed in any way or used commercially. http://creativecommons.org/licenses/by-nc-nd/4.0
spellingShingle 7200
Etemadi-Aleagha, Afshar
Akhgari, Maryam
Iravani, Fariba Sardari
Aluminum Phosphide Poisoning-Related Deaths in Tehran, Iran, 2006 to 2013
title Aluminum Phosphide Poisoning-Related Deaths in Tehran, Iran, 2006 to 2013
title_full Aluminum Phosphide Poisoning-Related Deaths in Tehran, Iran, 2006 to 2013
title_fullStr Aluminum Phosphide Poisoning-Related Deaths in Tehran, Iran, 2006 to 2013
title_full_unstemmed Aluminum Phosphide Poisoning-Related Deaths in Tehran, Iran, 2006 to 2013
title_short Aluminum Phosphide Poisoning-Related Deaths in Tehran, Iran, 2006 to 2013
title_sort aluminum phosphide poisoning-related deaths in tehran, iran, 2006 to 2013
topic 7200
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635777/
https://www.ncbi.nlm.nih.gov/pubmed/26402837
http://dx.doi.org/10.1097/MD.0000000000001637
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