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Carving out its niche: A role for carbonic anhydrase IX in pre-metastatic niche development

Primary tumor-associated hypoxia stimulates the production of secreted factors that mobilize bone marrow-derived cells, including immunomodulatory myeloid-derived suppressor cells (MDSCs) to pre-metastatic niches. We recently found that the hypoxia-induced enzyme carbonic anhydrase IX (CAIX) promote...

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Detalles Bibliográficos
Autores principales:	Chafe, Shawn C, Dedhar, Shoukat
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2015
Materias:	Author's View
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635843/ https://www.ncbi.nlm.nih.gov/pubmed/26587316 http://dx.doi.org/10.1080/2162402X.2015.1048955

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