A high density of tertiary lymphoid structure B cells in lung tumors is associated with increased CD4(+) T cell receptor repertoire clonality

T and B cell receptor (TCR and BCR, respectively) Vβ or immunoglobulin heavy chain complementarity-determining region 3 sequencing allows monitoring of repertoire changes through recognition, clonal expansion, affinity maturation, and T or B cell activation in response to antigen. TCR and BCR repert...

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Detalles Bibliográficos
Autores principales: Zhu, Wei, Germain, Claire, Liu, Zheng, Sebastian, Yinong, Devi, Priyanka, Knockaert, Samantha, Brohawn, Philip, Lehmann, Kim, Damotte, Diane, Validire, Pierre, Yao, Yihong, Valge-Archer, Viia, Hammond, Scott A, Dieu-Nosjean, Marie-Caroline, Higgs, Brandon W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635865/
https://www.ncbi.nlm.nih.gov/pubmed/26587322
http://dx.doi.org/10.1080/2162402X.2015.1051922

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