p38 MAPK mediates glial P2X7R-neuronal P2Y1R inhibitory control of P2X3R expression in dorsal root ganglion neurons

BACKGROUND: We have previously shown that endogenously active purinergic P2X7 receptors (P2X7Rs) in satellite glial cells of dorsal root ganglia (DRGs) stimulate ATP release. The ATP activates P2Y1Rs located in the enwrapped neuronal somata, resulting in down-regulation of P2X3Rs. This P2X7R-P2Y1-P2...

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Detalles Bibliográficos
Autores principales: Chen, Yong, Li, Guangwen, Huang, Li-Yen Mae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635984/
https://www.ncbi.nlm.nih.gov/pubmed/26542462
http://dx.doi.org/10.1186/s12990-015-0073-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635984/
https://www.ncbi.nlm.nih.gov/pubmed/26542462
http://dx.doi.org/10.1186/s12990-015-0073-7

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