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Semaphorin 4A as novel regulator and promising therapeutic target in rheumatoid arthritis
Rheumatoid arthritis (RA) is a systemic autoimmune disease manifesting in joint destruction. The recognized hallmark of RA pathogenesis is the involvement of immune cells which produce many mediators potentiating an inflammatory environment. RA synovial fibroblasts (RASFs) contribute significantly t...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635990/ https://www.ncbi.nlm.nih.gov/pubmed/26542940 http://dx.doi.org/10.1186/s13075-015-0846-4 |