Cargando…
Rapid Memory T-cell Reconstitution Recapitulating CD45RA-depleted Haploidentical Transplant Graft Content in Patients with Hematologic Malignancies
T-cell depletion of an HLA-haploidentical graft is often used to prevent graft-vs.-host disease (GvHD), but the procedure may lead to increased graft failure, relapse, and infections due to delayed immune recovery. We hypothesized that selective depletion of the CD45RA+ subset can effectively reduce...
Autores principales: | Triplett, Brandon M, Shook, David R, Eldridge, Paul, Li, Ying, Kang, Guolian, Dallas, Mari, Hartford, Christine, Srinivasan, Ashok, Chan, Wing Keung, Suwannasaen, Duangchan, Inaba, Hiroto, Pui, Ching-Hon, Leung, Wing |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636007/ https://www.ncbi.nlm.nih.gov/pubmed/25665048 http://dx.doi.org/10.1038/bmt.2014.324 |
Ejemplares similares
-
Improved survival rate in T-cell depleted haploidentical hematopoietic cell transplantation over the last 15 years at a single institution
por: Mamcarz, Ewelina, et al.
Publicado: (2019) -
Selective depletion of naïve T cells by targeting CD45RA
por: Naik, Swati, et al.
Publicado: (2023) -
Chimeric antigen receptor-redirected CD45RA-negative T cells have potent antileukemia and pathogen memory response without graft-versus-host activity
por: Chan, W K, et al.
Publicado: (2015) -
A phase II clinical trial of adoptive transfer of haploidentical natural killer cells for consolidation therapy of pediatric acute myeloid leukemia
por: Nguyen, Rosa, et al.
Publicado: (2019) -
Novel treatment of severe combined immunodeficiency utilizing ex-vivo T-cell depleted haploidentical hematopoietic stem cell transplantation and CD45RA+ depleted donor lymphocyte infusions
por: Brodszki, Nicholas, et al.
Publicado: (2016)