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Translocation-coupled DNA cleavage by the Type ISP restriction-modification enzymes
Endonucleolytic double-strand DNA break production requires separate strand cleavage events. Although catalytic mechanisms for simple dimeric endonucleases are available, there are many complex nuclease machines which are poorly understood in comparison. Here we studied the single polypeptide Type I...
Autores principales: | Chand, Mahesh Kumar, Nirwan, Neha, Diffin, Fiona M., van Aelst, Kara, Kulkarni, Manasi, Pernstich, Christian, Szczelkun, Mark D., Saikrishnan, Kayarat |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636054/ https://www.ncbi.nlm.nih.gov/pubmed/26389736 http://dx.doi.org/10.1038/nchembio.1926 |
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