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Evaluation of High-Throughput Genomic Assays for the Fc Gamma Receptor Locus
Cancer immunotherapy has been revolutionised by the use monoclonal antibodies (mAb) that function through their interaction with Fc gamma receptors (FcγRs). The low-affinity FcγR genes are highly homologous, map to a complex locus at 1p23 and harbour single nucleotide polymorphisms (SNPs) and copy n...
Autores principales: | Hargreaves, Chantal E., Iriyama, Chisako, Rose-Zerilli, Matthew J. J., Nagelkerke, Sietse Q., Hussain, Khiyam, Ganderton, Rosalind, Lee, Charlotte, Machado, Lee R., Hollox, Edward J., Parker, Helen, Latham, Kate V., Kuijpers, Taco W., Potter, Kathleen N., Coupland, Sarah E., Davies, Andrew, Stackpole, Michael, Oates, Melanie, Pettitt, Andrew R., Glennie, Martin J., Cragg, Mark S., Strefford, Jonathan C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636148/ https://www.ncbi.nlm.nih.gov/pubmed/26545243 http://dx.doi.org/10.1371/journal.pone.0142379 |
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