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Deciphering Transcriptional Dynamics In Vivo by Counting Nascent RNA Molecules
Deciphering how the regulatory DNA sequence of a gene dictates its expression in response to intra and extracellular cues is one of the leading challenges in modern genomics. The development of novel single-cell sequencing and imaging techniques, as well as a better exploitation of currently availab...
Autores principales: | Choubey, Sandeep, Kondev, Jane, Sanchez, Alvaro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636183/ https://www.ncbi.nlm.nih.gov/pubmed/26544860 http://dx.doi.org/10.1371/journal.pcbi.1004345 |
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