Kaposi’s Sarcoma-Associated Herpesvirus (KSHV) Induces the Oncogenic miR-17-92 Cluster and Down-Regulates TGF-β Signaling

KSHV is a DNA tumor virus that causes Kaposi’s sarcoma. Upon KSHV infection, only a limited number of latent genes are expressed. We know that KSHV infection regulates host gene expression, and hypothesized that latent genes also modulate the expression of host miRNAs. Aberrant miRNA expression cont...

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Detalles Bibliográficos
Autores principales: Choi, Hong Seok, Jain, Vaibhav, Krueger, Brian, Marshall, Vickie, Kim, Chang Hee, Shisler, Joanna L., Whitby, Denise, Renne, Rolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636184/
https://www.ncbi.nlm.nih.gov/pubmed/26545119
http://dx.doi.org/10.1371/journal.ppat.1005255

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636184/
https://www.ncbi.nlm.nih.gov/pubmed/26545119
http://dx.doi.org/10.1371/journal.ppat.1005255

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