Identification of Small-Molecule Inhibitors against Meso-2, 6-Diaminopimelate Dehydrogenase from Porphyromonas gingivalis

Species-specific antimicrobial therapy has the potential to combat the increasing threat of antibiotic resistance and alteration of the human microbiome. We therefore set out to demonstrate the beginning of a pathogen-selective drug discovery method using the periodontal pathogen Porphyromonas gingi...

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Detalles Bibliográficos
Autores principales: Stone, Victoria N., Parikh, Hardik I., El-rami, Fadi, Ge, Xiuchun, Chen, Weihau, Zhang, Yan, Kellogg, Glen E., Xu, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636305/
https://www.ncbi.nlm.nih.gov/pubmed/26544875
http://dx.doi.org/10.1371/journal.pone.0141126

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