MHC Class I Expression by Donor Hematopoietic Stem Cells Is Required to Prevent NK Cell Attack in Allogeneic, but Not Syngeneic Recipient Mice

NK cells resist engraftment of syngeneic and allogeneic bone marrow (BM) cells lacking major histocompatibility (MHC) class I molecules, suggesting a critical role for donor MHC class I molecules in preventing NK cell attack against donor hematopoietic stem and progenitor cells (HSPCs), and their de...

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Detalles Bibliográficos
Autores principales: Hirata, Yuichi, Li, Hao-Wei, Takahashi, Kazuko, Ishii, Hiroshi, Sykes, Megan, Fujisaki, Joji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636372/
https://www.ncbi.nlm.nih.gov/pubmed/26544200
http://dx.doi.org/10.1371/journal.pone.0141785

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