Reduced D2/D3 Receptor Binding of Extrastriatal and Striatal Regions in Temporal Lobe Epilepsy

OBJECTIVE: Dopamine is an endogenous neuromodulator in cortical circuits and the basal ganglia. In animal models of temporal lobe epilepsy (TLE), seizure threshold is modulated to some extent by dopamine, with D1-receptors having a pro- and D2-receptors an anticonvulsant effect. We aimed to extend o...

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Detalles Bibliográficos
Autores principales: Bernedo Paredes, Viviane E., Buchholz, Hans-Georg, Gartenschläger, Martin, Breimhorst, Markus, Schreckenberger, Mathias, Werhahn, Konrad J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636381/
https://www.ncbi.nlm.nih.gov/pubmed/26544593
http://dx.doi.org/10.1371/journal.pone.0141098

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