Gene therapy with Neurogenin3, Betacellulin and SOCS-1 Reverses Diabetes in NOD Mice

Islet transplantation for Type 1 diabetes is limited by a shortage of donor islets and requirement for immunosuppression. We approached this problem by inducing in vivo islet neogenesis in NOD diabetic mice, a model of autoimmune diabetes. We demonstrate that gene therapy with helper-dependent adeno...

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Detalles Bibliográficos
Autores principales: Li, Rongying, Buras, Eric, Lee, Jeongkyung, Liu, Ruya, Liu, Victoria, Espiritu, Christie, Ozer, Kerem, Thompson, Bonnie, Nally, Laura, Yuan, Guoyue, Oka, Kazuhiro, Chang, Benny, Samson, Susan, Yechoor, Vijay, Chan, Lawrence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636470/
https://www.ncbi.nlm.nih.gov/pubmed/26172077
http://dx.doi.org/10.1038/gt.2015.62

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636470/
https://www.ncbi.nlm.nih.gov/pubmed/26172077
http://dx.doi.org/10.1038/gt.2015.62

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