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Gene therapy with Neurogenin3, Betacellulin and SOCS-1 Reverses Diabetes in NOD Mice

Islet transplantation for Type 1 diabetes is limited by a shortage of donor islets and requirement for immunosuppression. We approached this problem by inducing in vivo islet neogenesis in NOD diabetic mice, a model of autoimmune diabetes. We demonstrate that gene therapy with helper-dependent adeno...

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Detalles Bibliográficos
Autores principales:	Li, Rongying, Buras, Eric, Lee, Jeongkyung, Liu, Ruya, Liu, Victoria, Espiritu, Christie, Ozer, Kerem, Thompson, Bonnie, Nally, Laura, Yuan, Guoyue, Oka, Kazuhiro, Chang, Benny, Samson, Susan, Yechoor, Vijay, Chan, Lawrence
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636470/ https://www.ncbi.nlm.nih.gov/pubmed/26172077 http://dx.doi.org/10.1038/gt.2015.62

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