Treatment Following Intoxication With Lethal Dose of Paraquat: A Case Report and Review of Literature

INTRODUCTION: Paraquat is a widely used nitrogen-based herbicide which is lethal and causes multi-organ failure by accumulation in cells, which subsequently leads to death. CASE PRESENTATION: The present case report introduced a 25-year-old male with nausea, vomiting, and severe substernal burning s...

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Detalles Bibliográficos
Autores principales: Davarpanah, Mohammad Ali, Hosseinzadeh, Farideh, Mohammadi, S. Saeed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Kowsar 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636757/
https://www.ncbi.nlm.nih.gov/pubmed/26568853
http://dx.doi.org/10.5812/ircmj.19373
Descripción
Sumario:INTRODUCTION: Paraquat is a widely used nitrogen-based herbicide which is lethal and causes multi-organ failure by accumulation in cells, which subsequently leads to death. CASE PRESENTATION: The present case report introduced a 25-year-old male with nausea, vomiting, and severe substernal burning sensation after incidentally ingestion of a large amount of paraquat. The treatment of the patient with antioxidants (N-acetylcysteine and vitamin E) and hemodialysis started immediately after arriving to the hospital. CONCLUSIONS: Immediate and adequate use of antioxidants and hemodialysis has an undeniable and important role in survival of patients after ingestion of a large amount of paraquat.

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