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Improvement of spontaneous locomotor activity with JAK inhibition by JTE-052 in rat adjuvant-induced arthritis

BACKGROUND: Rheumatoid arthritis (RA) is a chronic inflammatory disease that leads to joint destruction, disability, and decreased quality of life (QOL). Inhibition of Janus kinase (JAK) signaling ameliorates articular inflammation and joint destruction in animal models of RA, but its effects on beh...

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Detalles Bibliográficos
Autores principales:	Tanimoto, Atsuo, Shinozaki, Yuichi, Nozawa, Keisuke, Kimoto, Yukari, Amano, Wataru, Matsuo, Akira, Yamaguchi, Takayuki, Matsushita, Mutsuyoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636776/ https://www.ncbi.nlm.nih.gov/pubmed/26546348 http://dx.doi.org/10.1186/s12891-015-0802-0

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