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p21 deficiency is susceptible to osteoarthritis through STAT3 phosphorylation
INTRODUCTION: Osteoarthritis (OA) is a multifactorial disease, and recent studies have suggested that cell cycle–related proteins play a role in OA pathology. p21 was initially identified as a potent inhibitor of cell cycle progression. However, it has been proposed that p21 is a regulator of transc...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636813/ https://www.ncbi.nlm.nih.gov/pubmed/26546411 http://dx.doi.org/10.1186/s13075-015-0828-6 |