Single-cell ChIP-seq reveals cell subpopulations defined by chromatin state

Chromatin profiling provides a versatile means to investigate functional genomic elements and their regulation. However, current methods yield ensemble profiles that are insensitive to cell-to-cell variation. Here we combine microfluidics, DNA barcoding and sequencing to collect chromatin data at si...

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Detalles Bibliográficos
Autores principales: Rotem, Assaf, Ram, Oren, Shoresh, Noam, Sperling, Ralph A., Goren, Alon, Weitz, David A., Bernstein, Bradley E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636926/
https://www.ncbi.nlm.nih.gov/pubmed/26458175
http://dx.doi.org/10.1038/nbt.3383

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636926/
https://www.ncbi.nlm.nih.gov/pubmed/26458175
http://dx.doi.org/10.1038/nbt.3383

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