Glucose Oxidase Induces Cellular Senescence in Immortal Renal Cells through ILK by Downregulating Klotho Gene Expression

Cellular senescence can be prematurely induced by oxidative stress involved in aging. In this work, we were searching for novel intermediaries in oxidative stress-induced senescence, focusing our interest on integrin-linked kinase (ILK), a scaffold protein at cell-extracellular matrix (ECM) adhesion...

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Detalles Bibliográficos
Autores principales: Troyano-Suárez, Nuria, del Nogal-Avila, María, Mora, Inés, Sosa, Patricia, López-Ongil, Susana, Rodriguez-Puyol, Diego, Olmos, Gemma, Ruíz-Torres, María Piedad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4637093/
https://www.ncbi.nlm.nih.gov/pubmed/26583057
http://dx.doi.org/10.1155/2015/416738

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